• Étude statistique et génétique de la schizophrénie dans la région de Constantine. 

  Boukhenaf, Yasmina; Rezgoun, Mohamed Larbi (Université Frères Mentouri Constantine 1, 2025-02-27)

  Introduction: schizophrenia is a complex psychiatric disorder with an etiology involving both environmental and genetic factors. Dopaminergic pathways, in particular, play a key role in its pathophysiology. Several ...
• Hypospadias, trouble du déterminisme du sexe 

  Laouar, Rania; Chellat, Djalila (Université Frères Mentouri Constantine 1, 2024-12-10)

  Introduction: Hypospadias, a complex urogenital malformation, raises significant concerns in pediatric urology due to its varied clinical implications. This thesis focused on a comprehensive approach, including an ...
• Les activités biologiques de l’extrait n-butanol de la plante médicinale endémique Moricandia arvensis vis-à-vis de la toxicité induite par Doxorubicine 

  Laraba, Meriem; Zama, Djamila (Université Frères Mentouri - Constantine 1, 2022-11-08)

  Doxorubicin is one of the most effective molecules used in chemotherapy for many types of cancer. Its clinical use is limited due to its severe toxicity to various organs. This research work focused on the investigation ...
• Étude des gènes de pathogénicité des souches d’Escherichia coli. 

  Meziani, Dahbia Yasmina; Rezgoun, Mohamed Larbi (Université Frères Mentouri - Constantine 1, 2023-04-18)

  Escherichia coli (E. coli) is the predominant species of the human gastrointestinal tract. It includes commensals as well as intestinal (InPEC) and extra-intestinal (ExPEC) pathogenic strains. ExPEC is a global public ...
• Etude de l’activité antioxydante et anti-inflammatoire d’extraits du lichen Parmotrema hypotropa sur un modèle de dermatite atopique chez la souris. 

  Tartouga, Maya Abir; El Ouar, Ibtissem (Université Frères Mentouri - Constantine 1, 2022-10-31)

  Lichens are organisms consisting of a fungus and algae or cyanobacteria living in symbiosis, they are used in traditional medicine throughout the world to treat many diseases such as respiratory, digestive, gynecological, ...
• Related-oxidative stress effect and biological activities of biomolecules from Algerian medicinal plants on the model of sera from Crohn’s disease patients. 

  Ramli, Imene; Zerizer, Sakina; Sechi, Leonardo Antonio (Université Frères Mentouri - Constantine 1, 2022)

  Here, an Ambrosia maritima and Bituminaria bituminosa were assessed for their phenolic profile composition, their potential antioxidant activity in vitro, and their cytoprotective effect in primary cultured human umbilical ...
• Profils phytochimiques LC-HRMS/MS et évaluation des activités antioxydante, anticholinestérase et anticancéreuse d’extraits et de fractions VLC de deux espèces du genre Linum (Linaeae). 

  Mouna, Ryma; Kabouche, Zahia (Université Frères Mentouri - Constantine 1, 2022-09-19)

  In this study, the ethyl acetate extract of two Linum species, L. numidicum Murb. (EAELN) and L. trigynum L. (EAELT) and the vacuum liquid chromatography (VLC) fractions of nBuOH extract of L. numidicum Murb. (BELN) were ...
• Inventaire des espèces de tiques (Arthropoda; Ixodinae) parasites des bovins et recherche de pathogène chez les tiques du genre Hyalomma au niveau de deux étages bioclimatiques. 

  Derradji, Lotfi; Kohil, Karima (Université Frères Mentouri - Constantine 1, 2022-09-14)

  Cattle are confronted to vector-borne diseases which reduce their growth, meat quality and milk production. Hard ticks are vectors of pathogens that cause bacterial, viral and parasitic diseases. In Algeria, parasitosis ...
• Biosystématique et écologie des orthoptères (Insecta, Orthoptera) dans l’Est algérien. 

  Derrouiche, Chahinez; Benkenana, Naima (Université Frères Mentouri - Constantine 1, 2022-07-13)

  A study of the orthopterans in the Eastern Algerian region was conducted with two main objectives : The first one is a survey of the fauna in 16 localities located in seven regions (Constantine, Batna, Mila, Khenchela, ...
• Étude du marqueur moléculaire EGFR dans le cancer broncho-pulmonaire. 

  Lahmadi, Mohamed; Beddar, Leila; Satta, Dalila (Université Frères Mentouri - Constantine 1, 2022-05-11)

  Lung cancer is the most commonly diagnosed cancer and the leading cause of cancerrelated death in men in Algeria. We carried out this study to assess clinicopathological aspects and risk factors of lung cancer in Eastern ...
• Le potentiel biologique préventif des polysaccharides issus de Gelidium spinosum récoltée des cotes de la région de Jijel. 

  Bouameur, Somia; Menad, Ahmed (Université Frères Mentouri - Constantine 1, 2022-05-18)

  The study of polysaccharides from algal flora covering the eastern Algerian coast remains minimal. For this reason, the present investigation is committed to exploring the antioxidant and anti-inflammatory potential of ...
• L’effet protecteur de l’extrait n-butanol des plantes médicinales « Saccocalyxs satureioides Coss et Dur et Genista vepres Pomel » vis-à-vis de la toxicité induite par l’isoniazide et la rifampicine. 

  Zehani, Lamia; Zama, Djamila (Université Frères Mentouri - Constantine 1, 2022-03-21)

  This study aims to evaluate the protective effect of n-BuOH extracts of two endemic medicinal plants ""Saccocalyxs satureioides and Genista vepres Pomel"" at a dose of (50 and 100 mg/kg) against hepatotoxicity and ...
• Etude cytogénétique et moléculaire des désordres du développement sexuel. 

  Zidoune, Housna; Chellat, Djalila; Mcelreavey, Kenneth (Université Frères Mentouri - Constantine 1, 2021-12-16)

  Disorders of sex determination/differentiation (DSD) comprise a heterogeneous group of congenital conditions in which chromosomal, gonadal or anatomical sex is discordant. In recent years, a number of new candidate genes ...
• Caractérisation moléculaire des gènes impliqués dans le cancer du rein. 

  Bensouilah, Fatima Zohra; Chellat, Djalila (Université Frères Mentouri - Constantine 1, 2021-09-26)

  Renal Cell Carcinoma (RCC) also called renal adenocarcinoma and accounts for 90 à 95% of primary malignant kidney tumors. It's the 14th most common cancer in the world, and the third of urological malignant tumors after ...
• Étude des gènes impliqués dans l’apparition du cancer du poumon. 

  Mimouni, Asma; Satta, Dalila (Université Frères Mentouri - Constantine 1, 2021-10-05)

  Due to its late discovery, bronchopulmonary cancer is a frequent cancer and poorly prognosticated, it may become a major health problem. Improving our knowledge of this cancer has become a major obligation in order to ...
• L’effet protecteur de l’extrait butanolique de la plante Centaurea maroccana contre la neurotoxicité induite par le cisplatine chez les souris. 

  Aissous, Imen; Benrebai, Mouad (Université Frères Mentouri - Constantine 1, 2021-09-30)

  This study aims to investigate the possible protective effects of n-BuOH extract of Centaurea maroccana Ball aerial parts against CP-induced neurotoxicity in male Wistar albino’s mice. The potential neuroprotective properties ...
• Effect of Phoenix dactylifera and Cydonia oblonga fruits on some diseases induced by stress. 

  Sakhri, Fatima Zahra; Zerizer, Sakina (Université Frères Mentouri - Constantine 1, 2021)

  Les événements stressants de la vie provoquent l’apparition des altérations au niveau du cerveau et peuvent conduire à plusieurs maladies mentales comme la dépression qui est l’une des pathologies mentales prévalentes dans ...
• Etude comparative de l’activité biologique de certaines plantes sur les maladies cardiovasculaires, induite par une hypercholestérolémie chez les souris. 

  Messaoudi, Sabar; Tebibel, S (Université Frères Mentouri - Constantine 1, 2021-03-10)

  Hyperlipidemia is a metabolic disease that groups quantitative increases in one or more lipoproteins in the blood plasma. Hypercholesterolemia is closely related to dyslipidemia consisting of a considerable increase in ...
• Profils épidémiologique et de susceptibilité génétique aux gliomes dans l’est Algérien. 

  Touati, Sabrina; Djekkoun, Rachid (Université Frères Mentouri - Constantine 1, 2021-03-25)

  Gliomas are the largest group of malignant brain tumors in adults. Epidemiological, clinical, translational, and fundamental research have made significant progress in our understanding of these tumors. Nevertheless, the ...
• Biological activities of medicinal plant extracts on arthritis induced by formalin and on tumoral process. 

  Slimani, wassila; Zerizer, Sakina (Université Frères Mentouri - Constantine 1, 2021-03-10)

  The natural products from plants and biological sources still remain an unlimited and uncondensed source of new phytochemicals and nutraceuticals. Medicinal plants have been prescribed and used widely for thousands of years ...

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