Abstract:
Helianthemum is a genus of plants including around 110 species, belongs to the
Cistaceae family also known as rock rose. This genus is growing in America, Europe and
Northern Africa. However, the Mediterranean region is considered its center of diversity.
Helianthemum sessiliflorum Pers. is one of species of this genus that showed previously anti inflammatory and analgesic activities. In addition, the aerial parts of this plant are
recommended in folk medicine in case of cutaneous lesion. The phytochemical investigation
of the AcOEt n-BuOH extracts of the aerial parts of H. sessiliflorum resulted in the
characterization of one new lignan named 1-O-acetyl prinsepiol, together with twenty seven
known bioactive compounds. Furthermore, the antioxidant and antibacterial activities of
different extracts of H. sessiliflorum were determined
