Abstract:
Our objective through the present study is to rein
vestigate one famous plant
used tremendously in our folk medicine, namely
Artemisia herba-alba.
In spite of the
numerous studies so far carried out on the consider
ed plant, our chemical screening
revealed two new sesquiterpene
lactones involved in
methylene chloride/methanol
extract of the aerial parts. The afforded new natur
al sesquiterpene lactones are 1b,9b-
diacetoxyeudesm-3-en-5a,6b,11bH-12,6-olide
(1)
and 1b,9b-diacetoxyeudesm-4-en-
6b,11bH-12,6-olide
(2)
together with 4 known compounds.
The structures of the compounds were determined by
comprehensive NMR
studies, including DEPT, COSY, NOESY, HMQC, HMBC an
d HRMS
