Etude phytochimique et biologique de l'espèce Thymus numidicus Poiret

Abstract

The thyme used since the antiquity in traditional medicine, is recognized by their therapeutic virtues. In this context, the present work concerns phytochemical and biological studies of an endemic species Thymus numidicus (Poiret). The phytochimical study led to the establishement six structures which were: Cirsilinéol, Cirsimaritin, Apigenin, Luteolin, Apigenin-7-O-glucuronide, Luteolin -7-O-glucuronide Antiradical potential of the n-BuOH extract was determined by the DPPH method, the order of IC50 is 35,08 μg/ ml. The analysis by GC and GC-MS of the essential oil of T. numidicus, obtained by water steam practice led to the identification of 48 compounds belonging essentially to the class of the monoterpenes. From which the most important is thymol (54,18%) and p-cymen (15,38%).