Investigation phytochimique de l’extrait n-butanol du Globularia alypum L

Abstract

This work is devoted to the phytochemical study of the Algerian plant named Globularia alypum L, belonging to the family Globulariaceae. This latter is widely distributed in the plant kingdom is known for its richness in secondary metabolites such as flavonoids phenylethanoids and iridoids. This chemical study has led to the isolation by chromatographic methods and characterization by spectroscopic methods focused mainly on the RMN1D and 2D, 3 secondary metabolites: 1) D- Mannitol 2) Syringin 3) Globularin The molecular structures of the isolated compounds were elucidated primarily through the use of techniques 1D and 2D NMR ( 1 H, 13 C J-modulated HH COSY, HSQC HMBC and NOESY), by mass spectrometry. The results of this work will be presented as follows:  The first chapter is devoted to a reminder bibliographic including a description of the botanical family and genus  The second chapter is devoted to a study of polyphenols and iridoids.  The phytochemical studies of the species will be presented in the third chapter.  The fourth chapter, results and discussion.