Synthèse, étude structurale et propriétés magnétiques et biologiques de nouveaux complexes de coordination à base d’hydrazides et de leurs dérivés

Abstract

This work is a part of structural, magnetic and biological study of new metal ion complexes with different types of hydrazide ligands and its derivatives according to different strategies. One of the main objectives of this thesis was to synthesize transition metal complexes with two hydrazides that have the same backbone with two different substituents in the aromatic rings. In order to study the effect of the architecture of the two ligands and more precisely the influence of the two 2ydroxyl and amino groups on the coordination mode, supramolecular structure and biological properties, several pathways have been explored which leads to interesting results. These complexes were the subject of a detailed radiocrystallographic study. The biological study shows that some complexes have antioxidant properties and others have antibacterial properties. The magnetic study on the Cr (III) dimer revealed that this complex exhibits antiferromagnetic interaction (J = -6.672 cm-1). This result is consistent with DFT calculations.