دراسة نواتج الأيض الثانوي و الفعالية البيولوجية للنبتتين Foeniculum vulgare Mill و Bunium incrassatum Boiss

Abstract

"In this study we have focused our interst on the secondary methabolites of two Algerian Apiacous plants in order to determinate the biological activity’s extracts of each of them. We have isolated and identified eighteen compounds. The compounds isolated from the aerial parts of Bunium incrassatum Boiss were identified for the first time in this genus and in this specie; Graveolone is a coumarin identified for the first time in the genus Foeniculum and in the specie Foeniculum Vulgare Mill. (44) Compounds have been identified in the Hydrodistilled essential oil of Bunium specie, by the use of GC and GC/MS analyse, with Caryophellene oxide (31.0%) and Nonacosane (44,7%) as main major compounds. The quantitative analysis of extracts by spectrophotometric methods with total polyphenols by the Folin Ciocalteu method and total flavonoids by the method of AlCl3 revealed the richness of acetate and butanol extracts in polyphenols and in flavonoids compared to the other extracts (MeOH and CHCl3). The Bunium extracts showed a significant antibactial activity against ATCC and Clinical bacteria (Gram + and Gram -) and also exhibited a good antioxidant activity by the use of DPPH and β – carotene"