دراسة فیتوكیمیائیة لنوعین من النبتات الطبیة ذات الأصل الجزائري من العائلة الخیمیة مع دراسة فعالیاتھما البیولوجیة

Abstract

The work done consist of the phytochemical and biological study of two species belonging to the family Apiaceae. The Phytochemical investigation conducted on ethyl acetate extracts and butanol of two species (Reutera lutea) and (Daucus aureus), has led to the separation of : Isoorientin, Isoorientin-6""-O-acetate, Luteolin-7-O-glucoside, Apigenin-7-O-glucoside and a isocoumarin and …, The separation of its compound has been achieved by the use of various chromatographic methods like : GC-MS, CC, CCM and HPLC. it is with spectroscopic methods (1H-RMN, 13C-RMN, HMQC, HMBC, ES) ) that could clarify all the structures of these metabolites. compounds Identified have never been isolated from the two species studied. The biological study in this work is interested in evaluating Anti-AGEs the activity of different extracts from the species Daucus aureus, and in particular extracts: hexane, chloroform, ethyl acetate and butanol. It is only the butanol and ethyl acetate extracts which showed significant activity.