Abstract:
The resistance of bacterial biofilms to antibiotics has led to the search for alternative approaches for
bioactive molecules of plant origin capable of destroying the biofilm. Essential oils are natural
compounds with important biological activities. This work aims to study the chemical composition, and
to evaluate the antibacterial and antibiofilm activities of 3 Essential oils extracted from plants from
Souk Al-Ahras. The antibacterial activities were assessed against 5 isolated clinical pathogens. The
essential oils were extracted by hydrodistillation Rosmarinus officinalis, Aloysia citrodora and
Artemisia herba alba oils provided a yield of (0.93%), (0.24%) and (0.87%), respectively. The study of
the antibacterial activities by the method of micro-dilution showed MICs values from 5 to 20 µl/ml.
The antibiofilm activity showed that essential oils exhibited antibiofilm activities even at sub-MIC
concentrations. This study illustrates the great potential for natural compounds from plants to be used
in the development of future phytotherapeutic antibiofilm agents
