Phytochemical and biological studies of Scabiosa stellata.L (Caprifoliaceae) & Sedum carealeum. Vahl ( Crassulaceae).
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his present work concerns the phytochemical and biological study of two Algerian plants Scabiosa stelatta.L and Sedum carealeum vahl. Chromatographic separations and purifications of these plants led to the isolation and identification of 18( S. stellata) and 3 compounds(S. carealeum). data.GC/MS analyses of hexane extract S. stellata allowed the identification of 43 metabolites belonging to several important families, fatty acids and their derivatives (87%) are the major ones, wherever 19 metabolites were identified and alkenes ( 60%) is the major family followed by 30% of fatty acids in hexane extract of second plant. S. stellata showed a good activity antioxidant with: DPPH, ABTS and Reducing Power tests. Compared with the other tested extracts, the n-butanol extract showed the highest activity. Using UHPLC-DAD-ESI/MSn, the knowledge of the S. stellata phenolic profile was successfully extended, for the first time establishing its content in important secondary metabolites, such as chlorogenic acids and flavonoids. Chlorogenic acids and flavonoids comprised more than 80% of the compounds found, which explains the recently reported antioxidant activity of this plant extract.
- Doctorat (Chimie)