Approche descriptive de la drépanocytose chez les enfants scolarisés à Sidi Amar (Annaba)
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Introduction: Sickle extremely heavy genetic and hereditary disease and complex becomes a public health problem in Algeria, it is characterized by strong painful thrust, and an obstacle to any sports activity in sickle cell children Methodology: This is a prospective study from 1 January 2011, to the 31 December 2013 on sickle-cell children 5 to 12 years in the city of Sidi Amar. Results: Basic Sample 8401 students (30) Case sickle cell that met our criteria were selected and used for our study in different schools Sidi Amar city of eastern Algeria. The average age of our children already known sickle cell by the hematology department of Sidi Amar is 8.20 ± 2.17 years and 8.61 ± 2.72 years for those recently found by our study. The average age of patients with sickle cell disease SS was 8.47 ± 1.56 years.The sex ratio was 1.1 with a male predominance of 53%. Families with modest and irregular income represent 84.05% 47% of the children in our study were born to consanguineous parents. SS form was predominant. Pallor and anemia dominated the clinical picture with 40% in outpatient and inpatient UDS respectively, followed asthenia 20% and jaundice with 16.66% .In addition there is an NFS disturbed namely decrease the GR rate = 2.69 × 109 elements, a rate of HGB = 6.8 g / dl, a = 32.3 MCHC g / dl and a MCV fl = 91. For a normochromic normocytic anemia. Electrophoresis Hb objective HbS rate = 87.6%. For the assessment of pain we used several scales EVENDOL, visual analogue scale VAS, topographic Design, Digital Scale EN, and the scale of FPS faces For the test of effort, our carriers of the sickle cell trait felt earlier and more intense fatigue, and the lower cardiovascular adaptation in carriers of sickle cell trait could be related to their hemoglobinopathies. Conclusion: the treatment of sickle cell disease requires the implementation of an action plan at the national level to improve the quality of life of sick children.
- Doctorat (Biochimie)