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Synthèse, caractérisation structurale et activité biologique des complexes de coordination à base de Sulfaméthoxazole.

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dc.contributor.author Habila, Imane
dc.contributor.author Bouacida, Sofiane
dc.date.accessioned 2022-12-08T08:10:54Z
dc.date.available 2022-12-08T08:10:54Z
dc.date.issued 2020-02-23
dc.identifier.uri http://depot.umc.edu.dz/handle/123456789/13282
dc.description.abstract During this research work carried out at the Environmental and Structural Molecular Chemistry Research Unit of the University Constantine 1, we have synthesized six new original compounds based on sulfamethoxazole ligand: four mononuclear complexes with zinc, copper and cobalt, also, two polymers based on cobalt and silver metals; The crystal structures of the latter were determined from low temperature x-ray diffraction data, they are characterized by preliminary analysis and by means of IR plus UV-Vis, accomplished by thermal analysis, studying hydrogen bond networks, also, Hirshfeld surface analysis and finalized by an entire calculation performed using the density functional theory DFT. The in-vitro antibacterial/antifungal activities of the free ligand (SMX) and its zinc and copper complexes were evaluated using the well- diffusion method in DMSO (dimethyl sulfoxide). Cotrimoxale is used as positive control to make meaningful comparison. fr_FR
dc.language.iso fr fr_FR
dc.publisher Université Frères Mentouri - Constantine 1 fr_FR
dc.subject Chimie: Chimie inorganique fr_FR
dc.subject Diffraction des rayons X fr_FR
dc.subject Sulfaméthoxazole fr_FR
dc.subject Métaux de transitions fr_FR
dc.subject Analyse de surface d'Hirshfeld fr_FR
dc.subject Activités antibactériennes/antifongiques fr_FR
dc.subject DFT. fr_FR
dc.subject X-rays diffraction fr_FR
dc.subject Transition metals fr_FR
dc.subject Hirshfeld surface analysis fr_FR
dc.subject Antibacterial/antifungal activities fr_FR
dc.subject حيود الأشعة السينية fr_FR
dc.subject السلفاميثوكسازول fr_FR
dc.subject المعادن الانتقالية fr_FR
dc.subject تحليل مساحة هارشفلد fr_FR
dc.subject الأنشطة المضادة للبكتيريا / المضادة للفطريات fr_FR
dc.subject نظرية الكثافة الوظيفية fr_FR
dc.title Synthèse, caractérisation structurale et activité biologique des complexes de coordination à base de Sulfaméthoxazole. fr_FR
dc.type Thesis fr_FR

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